Identification of motives mediating alternative functions of the neomorphic moonlighting TPPP/p25
نویسندگان
چکیده
منابع مشابه
Identification of motives mediating alternative functions of the neomorphic moonlighting TPPP/p25.
The disordered Tubulin Polymerization Promoting Protein (TPPP/p25), a prototype of neomorphic moonlighting proteins, displays physiological and pathological functions by interacting with distinct partners. Here the role of the disordered N- and C-termini straddling a middle flexible segment in the distinct functions of TPPP/p25 was established, and the binding motives responsible for its hetero...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
سال: 2014
ISSN: 0925-4439
DOI: 10.1016/j.bbadis.2014.01.009